Can hyaluronic acid (HA) fillers trigger issues or irritation years later?

Can hyaluronic prices trigger irritation years after injection? My dermatologist says that he has seen sufferers arrive after 6 years with this product after receiving a hyaluronic filler. Is there a solution to know if you’ll be a part of the individuals who reject the hundreds equivalent to restylane, vollure, and many others.? earlier than being injected?

So completely satisfied to have requested you the query! Some fillers of no HA are recognized to take action in uncommon circumstances. The issue virtually at all times seems as a "granuloma". What interprets to English signifies that when they’re biopsied, these bumps / bumps present some white blood cells and cells present in power irritation / irritation (eg, "large" cells). These appear like large pink and tender bumps on the face or wherever it has been injected. They’re very tough to deal with.

We additionally know that some sufferers with sure autoimmune ailments are barely extra prone to develop nodules. Logic. A few of us are extra susceptible to irritation.

Please don’t use everlasting masses. They sound good, but when there’s a downside, it is extremely tough to deal with if the realm isn’t reduce. And, as your face ages, it's unattainable to regulate and infrequently begins to look unusual. Expenses of lengthy length, however not everlasting, are preferable.

The injectable merchandise are:

Silicones (everlasting cost) – specifically no medical grade silicones nonetheless utilized in some elements of the world. Could trigger issues years later.
Artefill / Bellafill (everlasting cost) – microscopic plastic beads. Could trigger issues years later.
Radiesse (non-permanent) – cartilage as a calcium-based materials. That is often not an issue except you inject into areas for which it isn’t supposed. Inform your supplier in case you have an autoimmune illness.
Sculptra (not everlasting) – created from lactic acid. That is usually not an issue, besides within the case of improper mixing or injection, or use within the mistaken space of ​​the face. Inform your supplier in case you have an autoimmune illness.

Hyaluronic Acid Filling Brokers

I’ve by no means seen such circumstances reported in america. And … in case you persist with HA fillers manufactured by Galderma, Allergan, Merck, and many others., high quality management could be very rigorous and can be extraordinarily uncommon. The issue often comes from low-cost HA-based fillers manufactured in factories in China, Korea, Japanese Europe, and many others. the place the method of purification and high quality management is flawed or poor. Consequently, bacterial antigens are nonetheless current in these merchandise, inflicting irritation and granulomas.


Until you do a biopsy to substantiate the issue your dermatologist has been discussing, it is extremely tough to make certain of the issue. There are additionally deep infections (biofilms) that may happen round fillers for HA. These can final a very long time (years) and require particular remedy.

I hope it will show you how to,

Dr. Brandith Irwin

Founder, SkinTour

Director of the Madison Pores and skin & Laser Heart

Comply with my pores and skin ideas and journeys on Instagram!

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